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KMID : 0356720140300050222
Journal of the Korean Society of Coloproctology
2014 Volume.30 No. 5 p.222 ~ p.227
Effectiveness of Sodium Picosulfate/Magnesium Citrate (PICO) for Colonoscopy Preparation
Song Ki-Hwan

Suh Wu-Seok
Jeong Jin-Sik
Kim Dong-Sik
Kim Sang-Woo
Kwak Dong-Min
Hwang Jong-Seong
Kim Hyun-Jin
Park Man-Woo
Shim Min-Chul
Koo Ja-Il
Kim Jae-Hwang
Shon Dae-Ho
Abstract
Purpose: Bowel preparation with sodium phosphate was recently prohibited by the U.S. Food and Drug Administration. Polyethylene glycol (PEG) is safe and effective; however, it is difficult to drink. To identify an easy bowel preparation method for colonoscopy, we evaluated three different bowel preparation regimens regarding their efficacy and patient satisfaction.

Methods: In this randomized, comparative study, 892 patients who visited a secondary referral hospital for a colonoscopy between November 2012 and February 2013 were enrolled. Three regimens were evaluated: three packets of sodium picosulfate/magnesium citrate (PICO, group A), two packets of PICO with 1 L of PEG (PICO + PEG 1 L, group B), and two packets of PICO with 2 L of PEG (PICO + PEG 2 L, group C). A questionnaire survey regarding the patients¡¯ preference for the bowel preparation regimen and satisfaction was conducted before the colonoscopies. The quality of bowel cleansing was scored by the colonoscopists who used the Aronchick scoring scale and the Ottawa scale.

Results: The patients¡¯ satisfaction rate regarding the regimens were 72% in group A, 64% in group B, and 45.9% in group C. Nausea and abdominal bloating caused by the regimens were more frequent in group C than in group A or group B (P < 0.01). Group C showed the lowest preference rate compared to the other groups (P < 0.01). Group C showed better right colon cleansing efficacy than group A or group B.

Conclusion: Group A exhibited a better result than group B or group C in patient satisfaction and preference. In the cleansing quality, no difference was noted between groups A and C.
KEYWORD
Sodium picosulfate magnesium citrate, Satisfaction, Bowel preparation, Polyethylene glycols, Colonoscopy
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